According to NewAdvent.org, the bread that serves as the Eucharistic host during the Sacrament of the Eucharist is unadulterated wheat that is reduced to flour, diluted with water and baked with fire. That can be problematic for Catholics suffering from Celiac disease, an autoimmune disease that causes the body to attack the lining of the small intestine when proteins that are commonly found in wheat, rye and barley are ingested. Sufferers of Celiac disease must remove all wheat from their diets, and that includes the wheat hosts used during the administration of the Eucharist. Many Catholics with Celiac disease felt marginalized by their inability to accept the host during the Eucharist, which is such an important component of the Catholic faith. The United States Conference of Catholic Bishops determined that a low-gluten host developed by the Sisters of Perpetual Adoration in Clyde, Missouri, met the Code of Canon Law requirements regarding the host, making it possible for Catholics with Celiac disease to once again receive the Eucharist during Mass.